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Periodontitis, infection of the tooth-supporting tissues, results from the accumulation of pathogenic bacterial plaque at and below the gingival margin. The composition of the dental plaque community plays a central role in the etiology of periodontitis. The major periodontal pathogens are Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia (previously forsythensis), Campylobacter rectus, and Treponema denticola (2, 7, 22). In subgingival plaque, P. gingivalis, T. forsythia, and T. denticola have the strongest relation to periodontal tissue destruction.
Detection of Multiple Pathogenic Species in Saliva Is Associated with Periodontal Infectio
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