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Future Drug Targets in Periodontal Personalized Medicine—A Narrative Review

Periodontal diseases consist of a cluster of pathological conditions initiated by a complex microbial community causing inflammation within the supporting tissues of the teeth leading to attachment and tooth loss. Severe periodontitis is one of the leading causes 2 of 14 of tooth loss worldwide. Periodontitis is thought to affect 20–50% of the world’s population and is the 11th most prevalent disease globally. The main etiology of periodontal diseases can be attributed to bacterial biofilm. Several hosts and environmental factors such as genetic predisposition, lifestyle, oral hygiene, systemic conditions, and stress contribute to the onset and progression of periodontitis.

Yadalam_Patil_J of Personalized Medecine 2022
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