Future Drug Targets in Periodontal Personalized Medicine—A Narrative Review
Periodontal diseases consist of a cluster of pathological conditions initiated by a complex microbial community causing inflammation...
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Active matrix metalloproteinase-8: A potential biomarker oforal systemic link
This mini review aims to address some possible gaps in periodontal diagnosis in clinical studies particularly involving the oral-systemic...
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The OxyR homologue in Tannerella forsythia regulates expression of oxidative stress responses
and biofilm formation Tannerella forsythia is an anaerobic periodontal pathogen that encounters constant oxidative stress in the human...
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Subgingival microbial profile and production of proinflammatory cytokines in chronic periodontitis
Red Complex should be considered as major etiologic agents.
The increased amount of these periodontal pathogens…Causes a cascade of defense
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Heterogeneity in statin responses explained by variation in the human gut microbiome
Background: Statins remain one of the most prescribed medications worldwide. While effective in decreasing atherosclerotic cardiovascular...
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Intra- and Inter- Examiner Reliability in Classifying Periodontitis
According to the 2018 Classification of Periodontal Diseases Aim: To evaluate the inter-examiner reliability in classifying periodontitis...
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Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans
Imbalances in the oral microbial community and poor dental health have been associated with reduced cardiovascular and metabolic health....
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The efficacy of the adjunct use of subgingival air-polishing therapy with erythritol powder
compared to conventional debridement alone during initial non-surgical periodontal therapy To assess the efficacy of the adjunct use of a...
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The role of reactive oxygen and antioxidant species in periodontal tissue destruction
Periodontitis is a term used to describe an inflammatory process, initiated by the plaque biofilm, that leads to loss of periodontal...
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Effectiveness of probiotic, chlorhexidine and fluoride mouthwash against Streptococcus mutans
Chlorhexidine, sodium fluoride, and probiotic mouthwashes reduce plaque S. mutans levels. Probiotic mouthwash is effective and equivalent...
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The effect of supragingival glycine air-polishing on periodontitis during maintenance therapy
Glycine air polishing has been proved to be safe, comfortable and time-saving. Whether it could substitute ultrasonic scaling to remove...
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Clinical and microbiological effects of the supplementary use
of an erythritol powder air-polishing device in non-surgical periodontal therapy: a randomized clinical trial In this study, both SRP and...
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Efficacy of subgingival irrigation with 10% povidone-iodine as an adjunct to scaling
and root planing: A clinical and microbiological study To evaluate the effectiveness of subgingival irrigation with 10% povidone-iodine...
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The oral microbiome: Role of key organisms and complex networks in oral health and disease
The field of human microbiome research has undergone a revolution in its approach toward understanding how microorganisms influence the...
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Periodontal Disease: The Good, The Bad, and The Unknown
Source: Frontiers (2021) Periodontal disease is classically characterized by progressive destruction of the soft and hard tissues of the...
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Cetylpyridinium Chloride: Mechanism of Action, Antimicrobial Efficacy in Biofilms
And Potential Risks of Resistance Source: Antimicrobial Agents and Chemotherapy (2020) Institution of disinfection to drinking water...
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Survival of Oral Bacteria
Source: Crit Rev Oral Biol Med (1998) The global distribution of individual species of oral bacteria demonstrates their ability to...
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The Role of Hydrogen Peroxide in Environmental Adaptation of Oral Microbial Communities
Source: Oxid Med Cell Longev (2012) Oral bacteria residing in the supragingival biofilm have a remarkable degree of structural...
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Peroxide-Sensing Transcriptional Regulators in Bacteria
Source: J Bacteriol (2012) The ability to maintain intracellular concentrations of toxic reactive oxygen species (ROS) within safe limits...
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How microbes defend themselves from incoming hydrogen peroxide
Source: Front Immunol (2021) Microbes rely upon iron as a cofactor for many enzymes in their central metabolic processes. The reactive...
RESOURCES
Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.
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