Antimicrobial therapy in periodontitis: the use of systemic antimicrobials
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be efficacious if the biofilm is not disrupted?...
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Systemic antibiotics in periodontal therapy
Periodontitis is a biofilm infection with a mixed microbial aetiology. Periodontitis is generally treated by non-surgical mechanical...
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The Role of Oral Pathobionts in Dysbiosis during Periodontitis Development
Y. Jiao M. Hasegawa and N. Inohara (2014) Direct attack is not the only way that microbes cause disease. Previous studies on infectious...
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Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited
Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary arteries associated with atheroma formation,...
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Porphyromonas gingivalis: where do we stand in our battle against this oral pathogen?
Kaitlind C. Howard, Octavio A. Gonzalez and Sylvie Garneau-Tsodikova (2021) Periodontal diseases, such as gingivitis and periodontitis,...
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Bacterial Signatures in Thrombus Aspirates of Patients With Myocardial Infarction
Background—Infectious agents, especially bacteria and their components originating from the oral cavity or respiratory tract, have been...
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Oral microbiome: Unveiling the fundamentals
The oral cavity has the second largest and diverse microbiota after the gut harboring over 700 species of bacteria. It nurtures numerous...
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Active matrix metalloproteinase-8: A potential biomarker of oral systemic link
This mini review aims to address some possible gaps in periodontal diagnosis in clinical studies particularly involving the oral-systemic...
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Molecular Mechanisms Leading from Periodontal Disease to Cancer
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it has been recently associated with an...
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The Role of the Oral MicrobiotaRelated to Periodontal Diseases in Anxiety
Anxiety, Mood and Trauma, and Stress-Related Disorders The prevalence of anxiety, mood and trauma-and stress-related disorders are on the...
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What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?
Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can...
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Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications
The epidemiological, clinical interventional, and animal model-based studies discussed in the various chapters of this volume...
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The pathogenic mechanism of oral bacteria and treatment with inhibitors
The objective of this study was to introduce the evidence obtained through extensive research that periodontitis increases risk of many...
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More Than Just a Periodontal Pathogen – the Research Progress on Fusobacterium nucleatum
Fusobacterium nucleatumis a common oral opportunistic bacterium that can cause different infections. In recent years, studies have shown...
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Periodontal health, cognitive decline, and dementia
A systematic review and meta-analysis of longitudinal studies Poor periodontal health and tooth loss appear to increase the risk of both...
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Future Drug Targets in Periodontal Personalized Medicine—A Narrative Review
Periodontal diseases consist of a cluster of pathological conditions initiated by a complex microbial community causing inflammation...
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Active matrix metalloproteinase-8: A potential biomarker oforal systemic link
This mini review aims to address some possible gaps in periodontal diagnosis in clinical studies particularly involving the oral-systemic...
- 1 min
The OxyR homologue in Tannerella forsythia regulates expression of oxidative stress responses
and biofilm formation Tannerella forsythia is an anaerobic periodontal pathogen that encounters constant oxidative stress in the human...
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Heterogeneity in statin responses explained by variation in the human gut microbiome
Background: Statins remain one of the most prescribed medications worldwide. While effective in decreasing atherosclerotic cardiovascular...
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Intra- and Inter- Examiner Reliability in Classifying Periodontitis
According to the 2018 Classification of Periodontal Diseases Aim: To evaluate the inter-examiner reliability in classifying periodontitis...
RESEARCH
Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.
Research Menu
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