Shared detection of Porphyromonas gingivalis incohabiting family members: a systematic review
Introduction: Periodontitis is an inflammatory dysbiotic disease. Among putative dysbiosis causes, transmission of Porphyromonas...
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Comparison of periodontal microbiological patterns in Italian spouses
Purpose: The aim of this study is to evaluate whether periodontopathogens are transmitted from husband to wife or vice versa. Materials...
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The Role of the Oral Microbiome in the Development of Diseases
Periodontal disease (PD) is a complex and infectious illness that begins with a disruption of bacterial homeostasis. This disease induces...
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How Periodontal Disease and Presence of Nitric Oxide Reducing Oral Bacteria Affect Blood Pressure
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the maintenance of metabolic and cardiovascular...
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Microbiological goals of Periodontal Therapy
The vast majority of periodontal diseases are caused by microorganisms that reside at or below the gingival margin. The best way to...
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Long-term changes in the subgingival microbiota in patients with stage III–IV periodontitis
treated by mechanical therapy and adjunctive systemic antibiotics: A secondary analysis of a randomized controlled trial Aim: To explore...
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Direct Diagnostics Partners with Lincoln Memorial University-College of Dental Medicine
Direct Diagnostics (Direct Dx) is proud to announce their partnership with Lincoln Memorial University-College of Dental Medicine
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Antimicrobial therapy in periodontitis: the use of systemic antimicrobials
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be efficacious if the biofilm is not disrupted?...
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Systemic antibiotics in periodontal therapy
Periodontitis is a biofilm infection with a mixed microbial aetiology. Periodontitis is generally treated by non-surgical mechanical...
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Gum Disease Linked to Colorectal Cancer: COLDENT Study
Periodontal disease (PD) may increase the risk of sporadic colorectal cancer (CRC), findings from the population-based case-control...
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Periodontal disease as a risk factor for sporadic colorectal cancer: results from COLDENT study
Amal Idrissi Janati1 · Igor Karp2 · Jean‑François Latulippe3 · Patrick Charlebois4 · Elham Emami5 Colorectal cancer remains the top...
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The Role of Oral Pathobionts in Dysbiosis during Periodontitis Development
Y. Jiao M. Hasegawa and N. Inohara (2014) Direct attack is not the only way that microbes cause disease. Previous studies on infectious...
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Future Drug Targets in Periodontal Personalized Medicine—A Narrative Review
Periodontal disease is an infection-driven inflammatory disease characterized by the destruction of tooth-supporting tissues. The...
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Active matrix metalloproteinase-8: A potential biomarker of oral systemic link
This mini review aims to address some possible gaps in periodontal diagnosis in clinical studies particularly involving the oral-systemic...
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Molecular Mechanisms Leading from Periodontal Disease to Cancer
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it has been recently associated with an...
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Periodontal Inflammation and Systemic Diseases: An Overview
Periodontal disease (PD) is a general term encompassing a group of inflammatory pathologies that mainly include gingivitis and...
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The Role of the Oral MicrobiotaRelated to Periodontal Diseases in Anxiety
Anxiety, Mood and Trauma, and Stress-Related Disorders The prevalence of anxiety, mood and trauma-and stress-related disorders are on the...
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The Periodontopathic Pathogen, Porphyromonas gingivalis, Involves a Gut Inflammatory Response
Exacerbates Inflammatory Bowel Disease Periodontal disease (PD) is one of the most prevalent disorders globally and is strongly...
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Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications
The epidemiological, clinical interventional, and animal model-based studies discussed in the various chapters of this volume...
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Fusobacterium nucleatum: The Opportunistic Pathogen of Periodontal and Peri-Implant Diseases
Chen, Tao Shi , Yiling Li , LinyangHuang and Derong Yin *State Key Laboratory of Oral Diseases, National Clinical Research Center for...
RESEARCH
Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.
Research Menu
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