ADVANCING ORAL & SYSTEMIC HEALTH
Our mission is to give clinicians what they want: an inexpensive test focused on the five high-risk bacteria that is easy to read and comprehend, effortless to order, and results retuned in 48 hours.
MEET THE PATHOGENS
Primary cause of rapid alveolar bone loss in both children and adults, severe periodontitis and dental implant failure. Research studies have shown this pathogen increases risk for Cardiovascular Disease, Ischemic Stroke, Brain Abscesses, & Heart Infections
Primary cause of alveolar bone loss, periodontitis and implant failure. Research studies have shown this pathogen increases risk for Heart Attack, Ischemic Stroke, Type Two Diabetes, Dementia, Alzheimer's Disease, and other inflammatory diseases.
Primary cause of periodontitis and implant failure (peri-implantitus). Recent studies have also demonstrated its association with Dementia and Alzheimer's Disease.
Primary cause of periodontitis and implant failure (peri-implantitus). It's effect on other health issues is not as well known.
Associated with periodontitis and implant failure. Among the systemic issues is that it has been associated with preterm birth, low birth weight babies, and fetal death. This pathogen tends to facilitate the movement of other oral pathogens into the circulatory system.
NOT JUST ABOUT PERIODONTITIS
All five pathogens have been implicated in Peri-implantitis - inflammation of the soft tissue and bone loss that can lead to implant failure.
HIGH RISK PATHOGEN TEST
Easy to describe, explain, and market to the patient
Order via our user-friendly online provider portal
Fast medical history checkbox
Collect 1ml of patient saliva
Place in sealed container
Schedule FedEx pick-up
Results in 2 days
Share results with patients [secure and HIPAA compliant]
Implement treatment plan
Retest to ensure success
What Clinicians Are Saying About HR5
Scientific evidence has shown that these five bacterial pathogens are the most critical and highest risk for infection, inflammation, oral cavity damage, systemic consequences.
Focus makes the HR5 test easier to explain and market to patients, thereby increasing its use in the clinic.
As an efficient screening test, HR5 identifies low grade infections long before they present with visual sympthoms.
Accuracy starts with the latest qPCR technology but wins based on the molecular biochemistry skills of the scientific team and the superiority of the primers, probes, and signals.
We offer the most accurate test (lowest limit of detection) available for these bacteria in saliva. Ask us about it.
Accuracy means we find these harmful pathogens early, making them easier to treat and driving successful outcomes faster.
Price matters to all of us. A lower price-point means that it is easier to market to patients, offers more margin for practices, and increases use which will drive treatments and healthier patients.
We achieved lower cost through focus as well as technology improvements in throughput and operational efficiency
Our goal is to see this test one day covered by medical and dental insurance due to its significant impact on overall health.
For providers and patients alike, easy is about as important as price. Easy to order. Easy to read. Easy to explain. Easy to say yes.
What could be easier than collecting just 1ml of saliva from a patient. Hyper-efficient and results returned in just two days.
Equally important to us is designing the result format to be easy to understand and clearly identify the healthy ranges for each bacteria based on the latest research publications.
The verdict is in and the scientific research continues to implicate these five bacteria in an expanding horizon of oral and systemic health issues - acute and chronic.
Perhaps most compelling is the personalized treatment plan that can be created for each patient to manage their pathogen levels.
Our unique HR5 test can empower your practice to join the conversation for the evolving field of Oral-Systemic Health.
The Red Complex bacteria plus Fn (Aa, Pg, Tf, Td, Fn) at the Keystone pathogens that are most frequently mentioned as contributors to all Chronic Inflammatory Diseases including CVD, IS, DM, Cancers, Alzheimers's, etc.
-Dr. Tom Nabors
YALE SCHOOL OF PUBLIC HEALTH VERIFIED HR5 WITH 100% ACCURACY
Direct Diagnostics, as a transparent, science-based organization, recently submitted our HR5 test—the most accurate test available for bacteria in saliva, with the lowest limit of detection—to the Yale School of Public Health for verification purposes. Yale is one of the top salivary diagnostic testing programs in the world, and their results were astoundingly conclusive: the limit of detection (LOD) of HR5 qPCR was verified by the SalivaDirect Initiative, Yale School of Public Health. The results showed an unparalleled 100% level of accuracy, which is a result we are very excited to see and share.