direct diagnostics

2 min

Adjuvant use of multispecies probiotic in the treatment of peri-implant mucositis

A randomized controlled trial Aim: This randomized placebo-controlled clinical trial evaluated the effects of multispecies probiotic...

2 min

Rheumatoid Arthritis

Oral Biofilms from Symbiotic to Pathogenic Interactions and Associated Disease

Connection of Periodontitis and Rheumatic Arthritis by Peptidylarginine Deiminase A wide range of bacterial species are harbored in the...

1 min

Oral Microbiome

Heterogeneity in statin responses explained by variation in the human gut microbiome

Background: Statins remain one of the most prescribed medications worldwide. While effective in decreasing atherosclerotic cardiovascular...

1 min

Cancer

Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon

Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal adenomas and adenocarcinomas (CRC). In humans, high...

1 min

Brain Health

Porphyromonas gingivalis lipopolysaccharides act exclusively through

with a resilience between a mouse and human Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated...

1 min

Brain Health

Porphyromonas gingivalis-Induced Neuroinflammation in Alzheimer’s Disease

“Chronic” periodontitis and its keystone pathogen Porphyromonas gingivalis have repeatedly been associated with Alzheimer’s disease (AD)....

1 min

Brain Health

Alzheimer’s Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats

Is Serotype Dependent Periodontitis is a major risk factor for Alzheimer´s disease, and P. gingivalis is a keystone pathogen linking...

1 min

Rheumatoid Arthritis

Porphyromonas gingivalis and rheumatoid arthritis

Purpose of review: To explore the pathogenic association between periodontal disease and rheumatoid arthritis focusing on the role of...

1 min

Oral Microbiome

Intra- and Inter- Examiner Reliability in Classifying Periodontitis

According to the 2018 Classification of Periodontal Diseases Aim: To evaluate the inter-examiner reliability in classifying periodontitis...

1 min

Oral Microbiome

Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans

Imbalances in the oral microbial community and poor dental health have been associated with reduced cardiovascular and metabolic health....

1 min

Oral Microbiome

The role of reactive oxygen and antioxidant species in periodontal tissue destruction

Periodontitis is a term used to describe an inflammatory process, initiated by the plaque biofilm, that leads to loss of periodontal...

1 min

Cancer

Human oral microbiome and prospective risk for pancreatic cancer

This study provides supportive evidence that oral microbiota may play a role in the aetiology of pancreatic cancer.

1 min

Oral Microbiome

Effectiveness of probiotic, chlorhexidine and fluoride mouthwash against Streptococcus mutans

Chlorhexidine, sodium fluoride, and probiotic mouthwashes reduce plaque S. mutans levels. Probiotic mouthwash is effective and equivalent...

1 min

Cancer

Mechanisms of Oral Bacterial Virulence Factors in Pancreatic Cancer

Pancreatic cancer is a highly lethal disease, and most patients remain asymptomatic until the disease enters advanced stages. There is...

1 min

Oral Microbiome

The effect of supragingival glycine air-polishing on periodontitis during maintenance therapy

Glycine air polishing has been proved to be safe, comfortable and time-saving. Whether it could substitute ultrasonic scaling to remove...

1 min

Oral Microbiome

Clinical and microbiological effects of the supplementary use

of an erythritol powder air-polishing device in non-surgical periodontal therapy: a randomized clinical trial In this study, both SRP and...

1 min

News

Explore the Benefits of Salivary Testing Through Direct Diagnostics

"My career spans 54 years with 2 years in the US Navy and 36 years in private practice. While rotating through dental specialties in the...

1 min

Oral Microbiome

Efficacy of subgingival irrigation with 10% povidone-iodine as an adjunct to scaling

and root planing: A clinical and microbiological study To evaluate the effectiveness of subgingival irrigation with 10% povidone-iodine...

1 min

Cardiovascular

Presence of periodontal pathogenic bacteria in blood of patients with coronary artery disease

It has been hypothesised that oral bacteria can migrate, through the blood, from the mouth to the arterial plaques, thus exacerbating...

1 min

Cardiovascular

Inflammation in Periodontal Disease: Possible Link to Vascular Disease

Inflammation is a well-organized protective response to pathogens and consists of immune cell recruitment into areas of infection....

RESOURCES

Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.

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