Association between Polycystic Ovary Syndrome, OralMicrobiota and Systemic Antibody Responses
Polycystic ovary syndrome (PCOS) is a hormonal disorder of women that not only is the leading cause of infertility but also shows a...
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Bacterial Signatures in Thrombus Aspirates of Patients With Myocardial Infarction
Infectious agents, especially bacteria and their components originating from the oral cavity or respiratory tract, have been suggested to...
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Microbial Analysis of Umbilical Cord Blood Reveals Novel Pathogens Associated with Stillbirth
Stillbirths account for half of all perinatal mortality, but the underlying cause of a significant portion of the cases remains unknown....
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The OxyR homologue in Tannerella forsythia regulates expression of oxidative stress responses
and biofilm formation Tannerella forsythia is an anaerobic periodontal pathogen that encounters constant oxidative stress in the human...
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Microbial analysis of subgingival plaque samples compared to that of whole saliva in patients
with periodontitis Background: The detection of special bacterial species in patients with periodontitis is considered to be useful for...
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Detection of Multiple Pathogenic Species in Saliva is Associated with Periodontal Disease
Periodontitis, infection of the tooth-supporting tissues, results from the accumulation of pathogenic bacterial plaque at and below the...
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Population-Based Study of Salivary Carriage of Periodontal Pathogens in Adults
Large, general population-based data on carriage rates of periodontal pathogens hardly exist in the current literature. The objectives of...
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Microbial profile comparisons of saliva, pooled and site-specific subgingival samples
in periodontitis patients Objectives: The purpose of this study was to compare microbial profiles of saliva, pooled and site-specific...
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Yale School of Public Health Verified HR5 Test With 100% Accuracy
Direct Diagnostics, as a transparent, science-based organization, recently submitted our HR5 test—the most accurate test available for...
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Adjuvant use of multispecies probiotic in the treatment of peri-implant mucositis
A randomized controlled trial Aim: This randomized placebo-controlled clinical trial evaluated the effects of multispecies probiotic...
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Oral Biofilms from Symbiotic to Pathogenic Interactions and Associated Disease
Connection of Periodontitis and Rheumatic Arthritis by Peptidylarginine Deiminase A wide range of bacterial species are harbored in the...
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Heterogeneity in statin responses explained by variation in the human gut microbiome
Background: Statins remain one of the most prescribed medications worldwide. While effective in decreasing atherosclerotic cardiovascular...
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Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon
Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal adenomas and adenocarcinomas (CRC). In humans, high...
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Porphyromonas gingivalis lipopolysaccharides act exclusively through
with a resilience between a mouse and human Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated...
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Porphyromonas gingivalis-Induced Neuroinflammation in Alzheimer’s Disease
“Chronic” periodontitis and its keystone pathogen Porphyromonas gingivalis have repeatedly been associated with Alzheimer’s disease (AD)....
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Alzheimer’s Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats
Is Serotype Dependent Periodontitis is a major risk factor for Alzheimer´s disease, and P. gingivalis is a keystone pathogen linking...
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Porphyromonas gingivalis and rheumatoid arthritis
Purpose of review: To explore the pathogenic association between periodontal disease and rheumatoid arthritis focusing on the role of...
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Intra- and Inter- Examiner Reliability in Classifying Periodontitis
According to the 2018 Classification of Periodontal Diseases Aim: To evaluate the inter-examiner reliability in classifying periodontitis...
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Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans
Imbalances in the oral microbial community and poor dental health have been associated with reduced cardiovascular and metabolic health....
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The role of reactive oxygen and antioxidant species in periodontal tissue destruction
Periodontitis is a term used to describe an inflammatory process, initiated by the plaque biofilm, that leads to loss of periodontal...
RESEARCH
Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.
Research Menu
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