The Role of the Oral Microbiome in the Development of Diseases
Periodontal disease (PD) is a complex and infectious illness that begins with a disruption of bacterial homeostasis. This disease induces...
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How Periodontal Disease and Presence of Nitric Oxide Reducing Oral Bacteria Affect Blood Pressure
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the maintenance of metabolic and cardiovascular...
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Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition
The oral microbiome has the potential to provide an important symbiotic function in human blood pressure physiology by contributing to...
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Oral Microbiome and Nitric Oxide: the Missing Link in the Management of Blood Pressure
Having high blood pressure puts you at risk for heart disease and stroke, which are leading causes of death in the USA and worldwide. One...
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Microbiological goals of Periodontal Therapy
The vast majority of periodontal diseases are caused by microorganisms that reside at or below the gingival margin. The best way to...
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Direct Diagnostics and CRET Partnership Promotes Dental Education Advancements
Through Salivary Diagnostics Direct Diagnostics is thrilled to announce its membership with the Center for Research & Education in...
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Long-term changes in the subgingival microbiota in patients with stage III–IV periodontitis
treated by mechanical therapy and adjunctive systemic antibiotics: A secondary analysis of a randomized controlled trial Aim: To explore...
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Effects on clinical outcomes of adjunctive moxifloxacin versus amoxicillin plus metronidazole
in periodontitis patients harboring Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythia:...
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Antimicrobial therapy in periodontitis: the use of systemic antimicrobials
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be efficacious if the biofilm is not disrupted?...
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Systemic antibiotics in periodontal therapy
Periodontitis is a biofilm infection with a mixed microbial aetiology. Periodontitis is generally treated by non-surgical mechanical...
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Gum Disease Linked to Colorectal Cancer: COLDENT Study
Periodontal disease (PD) may increase the risk of sporadic colorectal cancer (CRC), findings from the population-based case-control...
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Periodontal disease as a risk factor for sporadic colorectal cancer: results from COLDENT study
Amal Idrissi Janati1 · Igor Karp2 · Jean‑François Latulippe3 · Patrick Charlebois4 · Elham Emami5 Colorectal cancer remains the top...
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Association Between Periodontal Disease and Atherosclerotic Cardiovascular Diseases: Revisited
Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary arteries associated with atheroma formation,...
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Shift in the subgingival microbiome following scaling and root planing
in generalized aggressive periodontitis Guojing Liu, Xiaoqian Yu (2017) Scaling and root planing decreased periodontal pathogens in the...
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Porphyromonas gingivalis: where do we stand in our battle against this oral pathogen?
Kaitlind C. Howard, Octavio A. Gonzalez and Sylvie Garneau-Tsodikova (2021) Periodontal diseases, such as gingivitis and periodontitis,...
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Bacterial Signatures in Thrombus Aspirates of Patients With Myocardial Infarction
Background—Infectious agents, especially bacteria and their components originating from the oral cavity or respiratory tract, have been...
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Future Drug Targets in Periodontal Personalized Medicine—A Narrative Review
Periodontal disease is an infection-driven inflammatory disease characterized by the destruction of tooth-supporting tissues. The...
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Active matrix metalloproteinase-8: A potential biomarker of oral systemic link
This mini review aims to address some possible gaps in periodontal diagnosis in clinical studies particularly involving the oral-systemic...
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Molecular Mechanisms Leading from Periodontal Disease to Cancer
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it has been recently associated with an...
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Periodontal Inflammation and Systemic Diseases: An Overview
Periodontal disease (PD) is a general term encompassing a group of inflammatory pathologies that mainly include gingivitis and...
RESEARCH
Below is a curated selection of research papers, journal articles, and other significant publications related to the HR5 pathogens and Oral-Systemic Health.
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